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expression of four genes was increased (cyp11a1, rps9, sv2b, and egln2), and expression of 7 genes was decreased (vdac3, svs5, degs1, insl3, tmem97, hla-drb1, and hla-dr) in the old rat+krg group. red color indicates increase of gene expression whereas green color decrease of gene expression. ingenuity pathway analysis of genes between the old rat+krg and the young rat showed 2 networks. ingenuity pathway analysis of genes between the old rat+krg group and the old rat showed 2 networks. the intensity of the red colors indicates the degree of up regulation (chrnd, rpl10a, and serpinb6a) in the old rat compared to the young rat.
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: aging; cyp11a1; korean red ginseng; panax ginseng; system biology; testispmid: 23717070 pmcid: pmc3659540 doi: 10. commentshow to join pubmed commonshow to cite this comment:Ncbi > literature > pubmed.ça login para adicionar este vídeo à playlist "assistir mais tarde". however, the molecular mechanisms by which ginseng exerts these effects remain unknown.-utilitiesjournals in ncbi databasesmesh databasencbi handbookncbi help manualncbi newspubmedpubmed central (pmc)pubmed clinical queriespubmed healthall literature resources.
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& tutorialsncbi education pagencbi handbookncbi help manualncbi newsall training & tutorials resources. (b) pathways modulated significantly between the old rat+krg versus the young rat. the numbers under the gene name show change of gene expression in log2 basis. red ginseng up-regulates c21-steroid hormone metabolism via cyp11a1 gene in senescent rat testesj ginseng res. red ginseng up-regulates c21-steroid hormone metabolism via cyp11a1 gene in senescent rat testesj ginseng res.
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however, when genes in the old rat were compared with those in the old rat treated with krg, krg treatment up-regulated c21-steroid hormone metabolism. analysis of gene expression between the old rat treated with korean red ginseng (krg) versus the young rat. red ginseng up-regulates c21-steroid hormone metabolism via cyp11a1 gene in senescent rat testesj ginseng res..korean red ginseng up-regulates c21-steroid hormone metabolism via cyp11a1 gene in senescent rat testesj ginseng res.-regulation of dendritic cell maturation and immune system in the old rat treated with korean red ginseng (krg, young vs.
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(a) functions modulated significantly between the old rat+krg versus the young rat. ih1, kim sk, kim eh, kim sw, sohn sh, lee sc, choi s, pyo s, rhee dk. (b) the network with a score of 2 has 1 focus molecule, which has functions in cellular assembly and organization, cellular function and maintenance, and dermatological diseases. (basic local alignment search tool)blast (stand-alone)blast link (blink)conserved domain database (cdd)conserved domain search service (cd search)e-utilitiesprosplignprotein clustersprotein databasereference sequence (refseq)all proteins resources.ça login para adicionar este vídeo a uma playlist.
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(b) pathways modulated significantly between the old rat+krg group versus the old rat.(vídeo) ginseng - pra que serve e principais benefícios. resourceschemicals & bioassaysbiosystemspubchem bioassaypubchem compoundpubchem structure searchpubchem substanceall chemicals & bioassays resources. & rnablast (basic local alignment search tool)blast (stand-alone)e-utilitiesgenbankgenbank: bankitgenbank: sequingenbank: tbl2asngenome workbenchinfluenza virusnucleotide databasepopsetprimer-blastprosplignreference sequence (refseq)refseqgenesequence read archive (sra)spligntrace archiveunigeneall dna & rna resources. ingenuity pathway analysis of untreated aged rats versus aged rats treated with krg showed that the affected most was cyp11a1, responsible for c21-steroid hormone metabolism, and the top molecular and cellular functions are organ morphology and reproductive system development and function.
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analysisblast (basic local alignment search tool)blast (stand-alone)blast link (blink)conserved domain search service (cd search)genome protmapgenome workbenchinfluenza virusprimer-blastprosplignsplignall sequence analysis resources. - more resourcesfull text sourceseurope pubmed centralpubmed centralpubmed central canadamolecular biology databasesgene ontology annotations from this paper - gene ontologymiscellaneousnci cptac assay portalpubmed commons home. a reprodução automática é ativada, um vídeo sugerido será executado automaticamente em seguida. krg water extract prepared in feed pellets was administered orally into 12 month old rats for 4 months, and gene expression in testes was determined by microarray analysis. taken together, cyp11a1 expression is decreased in the aged rat, however, it is up-regulated by krg suggesting that krg seems enhance testes function via cyp11a1.
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expression of three genes was increased (syf2, plekha1, and arhgap32), and expression of 8 genes was decreased (col1a2, hsd11b1, insl3, orai1, proca1, collagen, pla2, and svs5) in the old rat+krg group. the green color denotes decreased gene expression (hbb, mba1, col1a2, pla2, proca1, tmem97, cyp11a1, and svs5).ça login para que sua opinião seja levada em conta. ingenuity pathway analysis of genes between the old rat and young rat was performed. total rna was isolated from testes of young rats (2 months old), old rats (16 months old) and old rats administered krg for 4 months, then 5 μg of isolated rna was converted to cdna using a reverse transcriptase.
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to clipboardadd to collectionsorder articlesadd to my bibliographygenerate a file for use with external citation management software.-regulation of c21-steroid hormone metabolism by korean red ginseng (krg) treatment (old rat vs. ingenuity pathway analysis of genes between the old rat versus the old rat+krg group was performed. of genomic structural variation (dbvar)database of genotypes and phenotypes (dbgap)database of single nucleotide polymorphisms (dbsnp)snp submission toolall variation resources. gene expression was increased (fundc2) in the old rat+krg group.